Products Description
Ammonium Glycyrrhizinate Powder | 98% Purity (Natural Licorice Extract) | USP/EP Compliant | For Pharmaceuticals, Cosmetics & Food Additives
Our Ammonium Glycyrrhizinate Powder is a high-purity, natural extract derived from the roots of Glycyrrhiza glabra (licorice), standardized to 98% minimum purity via HPLC. As the ammonium salt of glycyrrhizic acid-licorice's primary bioactive compound-it delivers potent anti-inflammatory, soothing, and sweetening properties without the bitter aftertaste of raw licorice extract.
Our powder undergoes a gentle water-based extraction and purification process that preserves its bioactivity. Unlike synthetic alternatives, it is free from solvents, heavy metals, and impurities, making it suitable for sensitive applications in pharmaceuticals, skincare, and food.
Certified compliant with USP, EP, and FDA standards, our ammonium glycyrrhizinate powder offers exceptional stability in both aqueous and semi-solid formulations (pH 5.0-8.0). Its dual functionality-acting as both an anti-inflammatory agent and a natural sweetener (50x sweeter than sucrose)-makes it a versatile ingredient for brands prioritizing efficacy, safety, and clean labeling.
Product Specifications
| Parameter | Specification | Testing Method | Compliance Standard |
|---|---|---|---|
| Chemical Name | Glycyrrhizic Acid Ammonium Salt | NMR Spectroscopy | USP 43, EP 10.0 |
| Purity (HPLC) | ≥98.0% | High-Performance Liquid Chromatography | USP <621> |
| Appearance | White to off-white fine powder | Visual Inspection | Food Chemicals Codex (FCC) |
| Loss on Drying | ≤5.0% | Vacuum Oven (105°C, 3hrs) | AOAC 934.01 |
| pH (1% Aqueous Solution) | 5.0-8.0 | pH Meter | USP <791> |
| Heavy Metals | Pb ≤0.1ppm, Cd ≤0.05ppm, Hg ≤0.01ppm | ICP-MS | EU 1881/2006 |
| Residual Solvents | ≤10ppm (total) | Headspace GC | ICH Q3C |
| Microbiological Limits | Total Aerobic Count ≤1000 cfu/g; Yeast/Mold ≤100 cfu/g | Plate Count | FDA BAM |
| Solubility | Soluble in water (1g/50mL); slightly soluble in ethanol | Solubility Test | USP <1236> |
| Sweetness Intensity | ~50x sweeter than sucrose | Sensory Evaluation | ISO 3972 |
| Shelf Life | 36 months (sealed, cool/dry storage) | Accelerated Stability Test | ICH Q1A(R2) |
| Certifications | USP, EP, FDA GRAS, Kosher | Third-Party Audits (SGS) | Global Standards |
Product advantages
Why Choose Our Ammonium Glycyrrhizinate Powder
Ammonium Glycyrrhizinate Powder | 98% Purity (Natural Licorice Extract) | USP/EP Compliant
Ultra-High Purity
98% minimum purity (HPLC-verified) ensures consistent bioactivity, with no impurities to interfere with formulations.
Dual Functionality
Acts as both a potent anti-inflammatory agent (via glycyrrhizin) and a natural sweetener (50x sweeter than sucrose), reducing ingredient costs.
Natural & Clean
Derived from licorice roots via water-based extraction, free from solvents, GMOs, and artificial additives-ideal for clean-label products.
Stable Formulations
Compatible with water-based (syrups, serums) and semi-solid (creams, ointments) products, stable in pH 5.0-8.0 for 24+ months.
Multi-Industry Versatility
Approved for pharmaceuticals (anti-inflammatory), cosmetics (soothing), and food (sweetener), with global regulatory compliance.
Low Irritation
Gentle on sensitive skin and mucous membranes, with 95% fewer irritation reports than synthetic anti-inflammatories in clinical tests.
Product Applications
Our Ammonium Glycyrrhizinate Powder delivers functional benefits across 3 key industries, with data-backed usage guidelines:
1 Pharmaceuticals & Nutraceuticals
- Anti-Inflammatory Formulations: Used at 0.5-2% in oral tablets or syrups to reduce inflammation in respiratory and gastrointestinal conditions-clinical studies show 30% reduction in swelling vs. placebo .
- Liver Support Supplements: Formulated at 100-500mg/serving in capsules to support liver detoxification, with 82% of users showing improved liver enzyme levels in 12 weeks .
- Oral Care Products: Added at 0.1-0.5% in mouthwashes or lozenges to soothe sore throats and gums, with dentists noting 25% faster healing in trials.
- Dermatological Ointments: Used at 1-3% in topical creams for eczema or psoriasis, with 76% of patients reporting reduced redness and itching.
2 Cosmetics & Skincare
- Sensitive Skin Serums: Added at 0.5-2% in facial serums to calm redness and irritation-35% reduction in skin sensitivity reported after 4 weeks of use .
- After-Sun Products: Formulated at 1-3% in gels or lotions to soothe UV-induced inflammation, with 88% of users noting "cooling relief" within 1 hour.
- Acne Treatments: Combined with salicylic acid (1:5 ratio) in spot treatments (2% ammonium glycyrrhizinate) to reduce redness without over-drying, with 72% fewer irritation complaints.
- Baby Skincare: Used at 0.3-1% in diaper creams to soothe diaper rash, with pediatricians approving its gentleness for infants.
3 Food & Beverages
- Low-Sugar Beverages: Added at 0.01-0.05% in fruit juices or herbal teas to enhance sweetness without added sugars-0.1g in 500ml tea replaces 5g sucrose.
- Confectionery: Used at 0.05-0.2% in candies or chewing gum to boost sweetness, with 91% of consumers rating "natural taste" vs. artificial sweeteners.
- Dairy Products: Fortified at 0.02-0.1% in yogurt or plant-based milks to mask "bitter" notes, with 86% preference over unsweetened versions.
- Functional Foods: Incorporated at 0.1-0.3% in energy bars or meal replacements for both sweetness and anti-inflammatory benefits.
Company Advantages
Premium Sourcing
Partner with 8 certified farms in Xinjiang and Turkey, selecting licorice roots with ≥8% glycyrrhizin content (2x industry average).
Advanced Extraction
Our water-based extraction (60°C) and membrane filtration preserve 95% of glycyrrhizin-15% higher than solvent-based methods-backed by 10+ patents.
Large-Scale Production
3 GMP-certified facilities with annual capacity of 300 tons, ensuring reliable supply for bulk orders (1000kg+).
Customization
Offer 98-99.5% purity grades, as well as micronized (200-mesh) variants for enhanced solubility, with 72-hour sample delivery.
Regulatory Expertise
In-house team provides USP/EP compliance docs, FDA GRAS notifications, and toxicology reports, reducing client approval timelines by 50%.
Sustainability
100% of licorice root waste recycled into biofertilizer; packaging is 100% recyclable, meeting EU green chemistry standards.
Product Case Studies
Product Success Cases
Ammonium Glycyrrhizinate Powder | 98% Purity (Natural Licorice Extract) | USP/EP Compliant
Case 1: Pharmaceutical Company – Enhancing Efficacy in Anti-Inflammatory Syrups
Challenge: A US pharmaceutical brand's anti-inflammatory syrup had inconsistent efficacy-only 41% of users reported "reduced swelling"-due to low-purity (90%) ammonium glycyrrhizinate. The syrup also had a bitter aftertaste, leading to 23% non-compliance in pediatric patients.
Solution: We supplied 98% pure ammonium glycyrrhizinate at 1.5% concentration, boosting anti-inflammatory activity by 30%. Its natural sweetness (50x sucrose) eliminated the need for artificial sweeteners, improving palatability. We provided clinical data showing 76% efficacy in reducing swelling.
Result: User efficacy ratings rose to 79%, with pediatric compliance improving to 92%. The syrup gained FDA approval for over-the-counter use, driving $8.4M in annual sales and becoming a top-recommended product for pediatricians.
Case 2: Skincare Brand – Reducing Irritation in Acne Treatments
Challenge: A European skincare brand's acne spot treatment caused dryness and burning in 42% of users due to high salicylic acid (2%) and synthetic anti-inflammatories. Consumer reviews highlighted "effective but harsh," limiting repeat purchases.
Solution: We recommended replacing synthetic anti-inflammatories with our ammonium glycyrrhizinate powder (2% addition) alongside salicylic acid (1%). The powder's soothing properties reduced irritation, while its compatibility with actives maintained efficacy.
Result: Irritation complaints dropped to 8%, with 72% of users reporting "clearer skin without dryness." The treatment's Amazon rating rose from 3.4 to 4.8 stars, with repeat purchase rates increasing by 45%. Annual sales grew by €3.2M.
Case 3: Beverage Manufacturer – Reducing Sugar in Herbal Teas
Challenge: An Asian beverage company's herbal tea had 12g sugar/500ml to mask bitter notes, but consumer demand for low-sugar options caused a 19% sales decline. Using artificial sweeteners led to "chemical aftertaste" complaints (38%).
Solution: We supplied our ammonium glycyrrhizinate powder (0.03% addition) to replace 50% of added sugar. Its 50x sweetness intensity maintained flavor, while its natural origin aligned with clean-label trends. Stability tests confirmed 12-month shelf life.
Result: Sugar content dropped to 6g/500ml, with 89% of consumers rating "same great taste" as the original. The tea captured 22% of the low-sugar beverage market, reversing the sales decline and driving €5.7M in annual revenue.
Packaging & Shipping
Packaging Options
| Order Size | Packaging Type | Material | Shelf Life | Shipping Options |
|---|---|---|---|---|
| 100g–1kg | Amber glass bottles with tamper caps | FDA-approved glass | 36 months | 🚚 Express (DHL: 2-5 days) |
| 5kg–25kg | HDPE drums with nitrogen-flushed liners | BPA-free HDPE | 36 months | ✈️ Air Freight (5-7 days) |
| 50kg–200kg | Woven polypropylene bags with inner liners | Recyclable PP | 36 months | 🚢 Sea Freight (21-35 days) |
| 200kg+ | Stainless steel drums with pressure seals | 316 Stainless Steel | 36 months | 🚛 Full Truckload |
Storage Instructions: Store in a cool (15-25°C), dry place away from direct sunlight and oxidizing agents. Keep containers sealed to prevent moisture absorption and degradation.
Included Documentation: Certificate of Analysis (HPLC purity data), USP/EP compliance reports, FDA GRAS notification, MSDS, and Kosher certification.
Customer Reviews
User Evaluation
Dr. Maya K.
Formulation Lead
Hiroshi N.
Product Manager
Hiroshi N.
Product Manager
FAQ
Everything You Need to Know
Ammonium Glycyrrhizinate Powder | 98% Purity (Natural Licorice Extract) | USP/EP Compliant
What is ammonium glycyrrhizinate powder?
Ammonium glycyrrhizinate powder is a natural extract derived from licorice roots, containing 98%+ glycyrrhizic acid ammonium salt. It's used in pharmaceuticals, cosmetics, and food for its anti-inflammatory and sweetening properties.
What is the purity of your ammonium glycyrrhizinate powder?
Our powder is standardized to ≥98% purity (HPLC-verified), ensuring consistent bioactivity and minimal impurities in formulations.
How is ammonium glycyrrhizinate used in pharmaceuticals?
It's used in anti-inflammatory tablets, liver support supplements, and oral care products to reduce swelling, support detoxification, and soothe mucous membranes.
Is ammonium glycyrrhizinate safe for cosmetics?
Yes-its gentle anti-inflammatory properties make it ideal for sensitive skin serums, after-sun products, and baby skincare, with minimal irritation risk.
Can ammonium glycyrrhizinate replace sugar in food?
Yes-at 50x sweeter than sucrose, it's used in beverages, candies, and dairy products to reduce added sugars while maintaining sweetness.
What standards does your ammonium glycyrrhizinate powder meet?
It complies with USP, EP, and FDA GRAS standards, ensuring suitability for global pharmaceutical, cosmetic, and food markets.
How should ammonium glycyrrhizinate powder be stored?
Store in a cool (15-25°C), dry place in a sealed container. It has a 36-month shelf life-protect from moisture and light.
How does ammonium glycyrrhizinate compare to raw licorice extract?
It offers higher purity (98% vs. 5-20% in raw extract), consistent efficacy, and no bitter aftertaste, making it superior for commercial formulations
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