Bulk Sodium Hyaluronate Powder (Hyaluronic Acid)

Pure Bio-Fermented Grade · Full Spectrum Molecular Weights (3kDa – 2.0MDa) · Ultra-Low Endotoxin & High Clarity Solution

Glucuronic Acid ≥ 44.0% Purity ≥ 95.0% Non-Animal Bio-Fermentation EP / USP Compliant

R&D Insights: Choosing the Right Molecular Weight for Your Formulation

Not All Hyaluronic Acid behaves the same in production.

If you have ever dealt with high-molecular-weight HA balling up during hydration, or low-molecular-weight HA causing unwanted sticky residues, you know that molecular weight control is everything. Standard HA raw materials often suffer from broad molecular weight distribution, leading to inconsistent viscosity and unpredictable skin penetration across production batches.

Our bio-fermented Sodium Hyaluronate is produced through advanced enzymatic cleavage and strict membrane filtration. We offer tailored molecular weight spectrums-from Oligo-HA (<10kDa) for deep dermal absorption to High MW (>1.5MDa) for superior film-forming hydration. Every batch is calibrated to give you precise rheological behavior and batch-to-batch stability.

Technical Specifications

INCI Name / CAS No.	Sodium Hyaluronate / 9004-61-9
Source & Grade	Streptococcus zooepidemicus Fermentation (Non-GMO / Non-Animal Grade)
Appearance & Form	White or off-white granular powder / fine powder, odorless
Molecular Weight Range	Oligo (<10kDa) \| Low (10k–200kDa) \| Medium (0.8M–1.5MDa) \| High (>1.5M–2.0MDa)
Glucuronic Acid Assay	≥ 44.0% (Corresponds to ≥ 95.0% Sodium Hyaluronate purity)
Transmittance (1% Sol.)	≥ 99.0% (Crystal clear aqueous solution)
Heavy Metals & Impurities	Heavy Metals < 10 ppm \| Pb < 2 ppm \| As < 1 ppm \| Protein < 0.1%
Microbial Control	Total Plate Count < 100 cfu/g; Moulds & Yeasts < 10 cfu/g; Pathogens Negative
Shelf Life & Storage	24 Months in sealed foil bags; store at 2–8°C for best molecular stability

Why Global Brands Choose Our Sodium Hyaluronate Powder

1. Strict Molecular Distribution Control

We tightly narrow the Mw range via specialized purification. This guarantees predictable hydration speed and consistent viscosity without lot-to-lot variances.

2. Ultra-High Clarity & Zero Residue

Achieves 99%+ optical clarity in 1% water solution. Leaves zero turbidity, cloudiness, or insoluble fibers in high-end cosmetic serums and eye drops.

3. High Purity & Low Endotoxin

Extremely low protein (<0.1%) and heavy metal content ensures high skin compatibility, drastically reducing irritation risks in sensitive skin products.

4. Excellent Water Retention Kinetics

Holds up to 1,000 times its own weight in water. Formulate silky, smooth emulsions with superior hydration performance and non-tacky finish.

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Sodium Hyaluronate Powder Product Application

Oligo & Super-Low MW (<10kDa – 100kDa)

Best for: Anti-aging serums, transdermal essences, deep hydration ampoules.
Penetrates the stratum corneum to repair deep skin barrier and stimulate collagen synthesis.

Medium MW (0.8MDa – 1.5MDa)

Best for: Daily moisturizing creams, lotions, facial masks, cleansers.
Provides long-lasting moisture retention with balanced texture and non-sticky sensory feel.

High MW (>1.5MDa – 2.0MDa)

Best for: Protective barrier creams, eye gels, anti-pollution skincare.
Forms a breathable protective layer on skin surface to shield against environmental pollutants and moisture loss.

Food & Nutriceutical Grade (Oral HA)

Best for: Beauty beverages, dietary capsules, joint care gummies.
Clinically proven to improve skin hydration from within and support joint lubrication.

Formulator & Industry Client Feedback

★★★★★

"We switched to their Oligo-HA (<10kDa) for our premium anti-aging serum line. The optical clarity in 1% aqueous solution is unbelievable-zero haze or cloudiness. Their batch COAs match our internal HPLC testing perfectly every time."

- Dr. Marcus V., R&D Director, Skincare Brand (USA)

★★★★★

"Dissolving high-molecular-weight HA used to be a bottleneck in our factory. Their granular-type high MW powder hydrates much faster without clumping up. It saved us significant mixing time per 500L batch."

- Elena R., Lead Formulator, Contract Manufacturer (Spain)

★★★★★

"Sourcing Food Grade HA with low endotoxin and clean microbial profiles is tough. Their 10kg drums arrive vacuum-sealed with full documentation. Highly reliable long-term supply partner!"

- Kenji T., Procurement Manager, Nutraceutical Brand (Japan)

★★★★★

"Great technical support team! They customized a specific 1.2MDa blend for our hydrogel mask product that achieved the exact skin feel we were aiming for. Fast sample dispatch too."

- Sophia M., Product Manager, Cosmeceuticals (South Korea)

Quality System & Compliance Documentation

✓ Global Standard Certifications

ISO9001, ISO22000, cGMP compliant. Certified Halal, Kosher, and Vegan / Cruelty-Free for worldwide regulatory clearance.

✓ Full Dossier & Analytical Support

Every shipment includes Batch COA, SEC-HPLC Molecular Weight Distribution Charts, Heavy Metal / Microbial Assay, MSDS, and Stability Data.

Packaging & Supply Chain Safety

Bulk & Sample Packaging

• Small Lot: 1 kg / Vacuum-Sealed Aluminum Foil Bag.
• Bulk Drum: 10 kg / 25 kg Fiber Drum with double PE inner moisture-barrier bags.
• Temperature-controlled cold chain packing options.

Global Logistics Options

• R&D Samples: 3–5 days via FedEx / DHL express.
• Commercial Orders: Air Freight / Express sea shipments.
• Temperature-monitored transit available upon request.

Frequently Asked Questions (FAQ)

Q1: How do I avoid clumping when dissolving high-molecular-weight HA powder?

A: We recommend pre-dispersing the powder in a polyol (such as Glycerin or Butylene Glycol) or Propanediol before adding water under high-speed stirring. Alternatively, allow the powder to sit overnight at low temperatures to hydrate naturally without aggressive shear.

Q2: What is the source of your Sodium Hyaluronate? Is it vegan and animal-free?

A: Yes, 100% animal-free. Our Sodium Hyaluronate is derived purely from bacterial fermentation (Streptococcus zooepidemicus) using plant-derived glucose media. It is 100% vegan, Non-GMO, and Halal/Kosher certified.

Q3: Can you customize a specific molecular weight range for our formulation?

A: Absolutely. While we keep standard Mw grades (3k, 10k, 100k, 1.2M, 1.8MDa) in stock, our R&D team can customize targeted molecular weight brackets according to your specific viscosity or skin-penetration targets.

Q4: How stable is your HA powder in high-temperature processing?

A: Sodium Hyaluronate is sensitive to prolonged heat above 60°C, which can cause chain cleavage and viscosity loss. We advise adding HA solution during the cooling phase (below 45°C) in hot-process emulsions.

Q5: What is the Minimum Order Quantity (MOQ) for trial and commercial orders?

A: We offer 1 kg vacuum bags as the MOQ for lab testing and pilot production. For commercial bulk orders, our standard drum packaging is 10 kg or 25 kg.

Q6: How can our lab request free samples for evaluation?

A: Simply click the button below to contact us. We provide 20g–50g free sample kits per molecular weight grade, complete with batch COA and HPLC testing spectrums for your formulation trial.

Need Specific Molecular Weight Samples for Your Lab?

Request complimentary 20g–50g sample kits with batch-specific COA, HPLC charts, and formulation guides.

Request Samples & Wholesale Price List

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