High-Purity Natural Apigenin Powder (Apigenin 98% HPLC)
Naturally Extracted from Premium Chamomile (Matricaria recutita) · Bioavailability-Enhanced Micro-Crystalline Granulation · Superior Batch-to-Batch Stability
R&D Insights: Overcoming Hydrophobic Limits for Sleep & Longevity Formulations
Technical notes from our botanical extraction & phytochemical formulation team.
Apigenin (4',5,7-trihydroxyflavone) is rapidly becoming the standout bioactive in sleep support, neuroprotection, and cellular longevity markets. However, formulators routinely run into two core physical hurdles: its inherently low aqueous solubility and extreme electrostatic static during encapsulation, which often leads to erratic capsule fill weights and slow absorption rates.
Our extraction laboratory overcomes these bottlenecks through a controlled alcohol-water recrystallization coupled with specialized physical micronization. This yields a vibrant, fine golden-yellow powder with uniform particle size distribution (over 90% through 100 mesh) and reduced static retention. The result is seamless high-speed capsule filling, excellent blending compatibility with Magnesium L-Threonate or L-Theanine, and reliable 98%+ HPLC potency.
Technical Specifications
| Product Name & CAS Number | Apigenin Powder (Natural Extract) | CAS No.: 520-36-5 |
| Botanical Source & Molecular Formula | Chamomile (Matricaria recutita L.) | C15H10O5 (MW: 270.24) |
| Standardized Assay (HPLC) | ≥ 98.0% Apigenin (Commercial production batches typically test between 98.3% – 99.1%) |
| Appearance & Particle Size | Light yellow to greenish-yellow crystalline powder | 100% through 80 Mesh, ≥ 90% through 100 Mesh |
| Melting Point & Loss on Drying | Melting Range: 345°C – 350°C | Loss on Drying ≤ 1.0% | Ash Content ≤ 0.5% |
| Solubility Profile | Soluble in DMSO and hot ethanol; sparingly soluble in water; highly stable in liposomal oil phases |
| Heavy Metals & Residues | Heavy Metals < 10 ppm | Pb < 1.0 ppm | As < 1.0 ppm | Cd < 0.5 ppm | Residual Ethanol < 3,000 ppm (USP) |
| Microbiological Control | Total Plate Count < 1,000 cfu/g | Yeast & Mold < 100 cfu/g | Salmonella & E. coli: Negative/10g |
| Storage & Expiration | 24 Months when stored in tight, light-resistant containers in a cool, dry warehouse environment. |
Frequently Asked Questions (FAQ)
Q1: How does your natural Apigenin extract compare against synthetic alternatives on the market?
A: Our Apigenin is 100% naturally derived from Chamomile flowers (Matricaria recutita). Synthetic versions often carry organic chemical impurities and lack consumer appeal on premium clean-label ingredient decks.
Q2: What is the recommended strategy for improving Apigenin's systemic bioavailability?
A: Because Apigenin is hydrophobic, formulators typically co-formulate it with dietary lipids, liposomal carriers, or synergistic flavones (like Quercetin) to optimize absorption through the gut wall.
Q3: How do you manage static electrical charge during processing and filling?
A: We apply a specialized physical milling and drying technique during post-crystallization processing. This yields uniform crystal boundaries and significantly reduces static buildup on automatic capsule machinery.
Q4: What is the ideal storage environment to prevent powder discoloration?
A: Apigenin is light-sensitive over extended periods. Store the powder in its original double-sealed anti-static PE bags inside a sealed fiber drum, away from direct sunlight and ambient moisture below 25°C.
Q5: How can our R&D team request a sample and lot COA for lab testing?
A: Simply complete the contact form below or email our sales team. We will send out a 100g sample kit along with full HPLC chromatograms and documentation within 24 to 48 hours.
Formulate Next-Gen Sleep & Longevity Products with Our Apigenin
≥98.0% Natural Chamomile HPLC Assay, low static behavior, clean solvent profile, and reliable bulk supply. Partner with an expert supplier today.
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