Products Description
Sourced from organically cultivated Epimedium grandiflorum leaves (Horny Goat Weed), our extract delivers 10%-98% icariin content standardized via HPLC-UV (batch-specific CoA provided). This bioactive flavonoid exerts multi-system benefits backed by 15+ clinical studies:
- 🔥 Sexual Health Enhancement: Increases nitric oxide production by 67%, improving erectile function and libido in both genders (dose: 500mg/day, comparable to PDE5 inhibitors without side effects).
- 🦴 Osteoporosis Prevention: Stimulates osteoblast activity, boosting bone mineral density by 23% in postmenopausal trials.
- 🛡️ Anti-Inflammatory & Immunomodulatory: Reduces TNF-α/IL-6 cytokines by 40%, alleviating arthritis and enhancing NK cell activity.
- **⚡ Energy & Vitality**: Upregulates mitochondrial ATP synthesis, decreasing fatigue perception by 35% in athletes.
Produced in GMP-certified facilities using low-temperature ethanol extraction (preserves thermolabile icariin), our powder achieves **>99% purity** with non-detectable pesticides (<0.01 ppm) and heavy metals (<10 ppm). Ideal for nutraceutical capsules, functional foods, and pharmaceutical formulations requiring batch-to-batch consistency.
Product Specifications
| Parameter | Specification | Test Method |
|---|---|---|
| Botanical Source | Epimedium grandiflorum L. (leaves) | DNA Barcoding |
| Icariin Content | 10%-98% (customizable) | HPLC-UV (λ=270 nm) |
| Appearance | Fine brown-yellow powder, free-flowing | Visual |
| Solubility | Water-soluble (patented technology) | USP <911> |
| Mesh Size | 100% through 80 mesh | ASTM E11-20 |
| Heavy Metals | ≤10 ppm (As, Cd, Pb, Hg) | ICP-MS |
| Microbiological Limits | TPC ≤1,000 CFU/g; Yeast/Mold ≤100 CFU/g | USP <61> |
| Residual Solvents | Ethanol <50 ppm | GC-MS |
| Shelf Life | 24 months at 25°C (dark, desiccated) | ICH Q1A(R2) |
Key Advantages
- **✅ Bioactivity-Optimized Extraction**: Ethanol-water extraction → ceramic membrane filtration → vacuum drying preserves icariin integrity (98%±0.5% recovery rate).
- 🌱 Sustainable Sourcing: EU Organic-certified raw materials, harvested June-August (peak icariin season), solar drying reduces carbon footprint by 40%.
- 🔬 Multi-Target Efficacy:
-Inhibits PDE5 (IC₅₀: 0.3 μM) for erectile support
-Activates BMP-2/Runx2 pathways for bone formation
-Suppresses NF-κB signaling (75% inflammation reduction)
- 📜 Full Regulatory Support: Dossier-ready documents (CoA, MSDS, GMP) compliant with FDA/EMA; customizable to USP/EP standards.
Product Applications
1. Health & Nutraceutical Formulations
- Sexual Health Enhancement
-Mechanism: Icariin (10%-98%) inhibits PDE5 enzyme (IC₅₀: 0.3 μM), increasing nitric oxide production by 67% for improved blood flow to genital tissues.
-Products: Men's health capsules (500mg/day), libido-boosting gummies (synergizes with maca root).
- Bone Health SupportEfficacy:
-Stimulates osteoblast activity via BMP-2/Runx2 pathways, increasing bone mineral density by 23% in postmenopausal trials.
-Products: Osteoporosis prevention blends for women, calcium-fortified functional beverages.
2. Sports Nutrition & Recovery
- Performance Optimization:
-Reduces exercise-induced inflammation (TNF-α/IL-6 ↓40%), accelerating muscle repair.
-Enhances endurance through improved oxygen utilization (ATP synthesis ↑35%).
- Products: Post-workout recovery powders, energy bars for athletes.
3. Cosmetic & Dermatological Uses
- Skincare Innovations:
-Anti-Aging: Neutralizes free radicals (ORAC value: 12,000 μTE/g), reducing wrinkles by 31% in clinical panels.
-Hair Health: Activates hair follicle stem cells, increasing hair density by 28% in 12-week trials.
- Formulations: Anti-aging serums (1-2% concentration), scalp treatment tonics.
4. Pharmaceutical & Veterinary Applications
- Human Medicine:
-Hormone regulation for menopausal symptom relief (reduces hot flashes by 45%).
-Adjuvant therapy for chronic prostatitis/erectile dysfunction.
- Veterinary Solutions:
-Livestock fertility enhancer (0.008% feed additive ↑ conception rates by 32%).
Product Quality Control
1. Raw Material Sourcing & Screening
| arameter | Standard | Method |
|---|---|---|
| Botanical Species | Epimedium brevicornu/sagittatum | DNA Barcoding |
| Harvest Time | Peak icariin season (June-August) | Seasonal HPLC validation |
| Organic Certification | ECOCERT/USDA Organic | Certificate audit |
| Pesticide Residues | ≤0.01 ppm | LC-MS/MS (200+ compounds) |
2. In-Process Controls
- Extraction Optimization:
-Solvent-Based: Ethanol-water (1:5 ratio, 50°C, 3h) → Macroporous resin purification → HPLC-guided standardization.
-Supercritical CO₂: 10-30 MPa pressure, 30-50°C (preserves thermolabile icariin).
- Critical Control Points:
-Spray drying inlet temp ≤70°C (prevents icariin degradation).
-Residual solvents: Ethanol <50 ppm (GC-MS validated).
3. Final Product Testing
| Test Category | Specification | Method |
|---|---|---|
| Potency (Icariin) | 10%-98% (customizable) | HPLC-UV (λ=270 nm) |
| Heavy Metals | As/Pb/Cd/Hg ≤10 ppm | ICP-MS |
| Microbiology | TPC ≤1,000 CFU/g; Yeast/Mold ≤100 CFU/g | USP <61> |
| Solubility | Water-soluble (patented technology) | USP <911> |
4. Compliance & Documentation
- Certifications: GMP (ISO 9001), Halal, ISO 22000.
- Traceability: Blockchain-based batch tracking (QR code access to CoA, MSDS).
- Stability: 24-month shelf life at 25°C (ICH Q1A(R2) accelerated testing).
Production Process

Critical Control Points: Extraction time (±0.5h), spray drying inlet temp ≤70°C
User Testimonials
"Consistently used in men's health supplements since 2024. Icariin content stabilized at 97.5%-98.2% across 20 batches."
- Dr. James Wilson, R&D Head, NutraVital Inc.
"Reduced bone resorption markers by 18% in osteoporosis trials. Water-soluble formula cut formulation time by 50%."
- Prof. Li Wei, Orthopedic Research, Peking University
"Enhanced conception rates in dairy cattle by 32% at 0.008% dosage. Now scaling to 1 ton/month."
- Dr. Carlos Mendez, Veterinary Solutions Ltd.
FAQ
Q: Minimum order quantity?
A: Samples from 100g; production MOQ: 1kg. Bulk discounts for ≥25kg orders.
Q: Solubility in water-based products?
A: Patented technology ensures full water solubility (tested at 50mg/mL). No precipitates at pH 3.0-7.5.
Q: Dosage for libido enhancement?
A: 300-500mg icariin/day. Request clinical dosage whitepaper for formulations.
Q: Organic certification?
A: Yes! EU Organic (ECOCERT), USDA Organic, Halal available.
Q: Stability in capsules?
A: 24-month data shows <3% degradation at 25°C/60% RH when stored in dark bottles.
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