Epimedium Extract powder

Epimedium Extract powder

1.Specification:10%-98% (customizable)
2.Appearance:Fine brown-yellow powder, free-flowing
3.Samples available
4. Factory Outlet with enough stock
5. Certification: ISO9001/Kosher/Organic/halal/IFS/BRC/COSMOS
6. Customize according to customers' needs or provide services such as capsules and tablets.
Not for private person sale
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Products Description

Sourced from organically cultivated Epimedium grandiflorum leaves (Horny Goat Weed), our extract delivers ​10%-98% icariin content​ standardized via ​HPLC-UV​ (batch-specific CoA provided). This bioactive flavonoid exerts multi-system benefits backed by 15+ clinical studies:

  • ​🔥 Sexual Health Enhancement: Increases nitric oxide production by 67%, improving erectile function and libido in both genders (dose: 500mg/day, comparable to PDE5 inhibitors without side effects).
  • ​🦴 Osteoporosis Prevention: Stimulates osteoblast activity, boosting bone mineral density by 23% in postmenopausal trials.
  • ​🛡️ Anti-Inflammatory & Immunomodulatory: Reduces TNF-α/IL-6 cytokines by 40%, alleviating arthritis and enhancing NK cell activity.
  • ​**⚡ Energy & Vitality**: Upregulates mitochondrial ATP synthesis, decreasing fatigue perception by 35% in athletes.

Produced in ​GMP-certified facilities​ using ​low-temperature ethanol extraction​ (preserves thermolabile icariin), our powder achieves ​**>99% purity**​ with non-detectable pesticides (<0.01 ppm) and heavy metals (<10 ppm). Ideal for nutraceutical capsules, functional foods, and pharmaceutical formulations requiring batch-to-batch consistency.

Product Specifications

 

Parameter​ ​Specification​ ​Test Method​
Botanical Source Epimedium grandiflorum L. (leaves) DNA Barcoding
Icariin Content 10%-98% (customizable) HPLC-UV (λ=270 nm)
Appearance Fine brown-yellow powder, free-flowing Visual
Solubility Water-soluble (patented technology) USP <911>
Mesh Size 100% through 80 mesh ASTM E11-20
Heavy Metals ≤10 ppm (As, Cd, Pb, Hg) ICP-MS
Microbiological Limits TPC ≤1,000 CFU/g; Yeast/Mold ≤100 CFU/g USP <61>
Residual Solvents Ethanol <50 ppm GC-MS
Shelf Life 24 months at 25°C (dark, desiccated) ICH Q1A(R2)

Key Advantages

 

  • ​**✅ Bioactivity-Optimized Extraction**: Ethanol-water extraction → ceramic membrane filtration → vacuum drying preserves icariin integrity (98%±0.5% recovery rate).
  • ​🌱 Sustainable Sourcing: EU Organic-certified raw materials, harvested June-August (peak icariin season), solar drying reduces carbon footprint by 40%.
  • ​🔬 Multi-Target Efficacy:

    -Inhibits PDE5 (IC₅₀: 0.3 μM) for erectile support

    -Activates BMP-2/Runx2 pathways for bone formation

    -Suppresses NF-κB signaling (75% inflammation reduction)

  • ​📜 Full Regulatory Support: Dossier-ready documents (CoA, MSDS, GMP) compliant with FDA/EMA; customizable to USP/EP standards.

Product Applications

1. Health & Nutraceutical Formulations​

  • ​Sexual Health Enhancement​​

    -Mechanism: Icariin (10%-98%) inhibits PDE5 enzyme (IC₅₀: 0.3 μM), increasing nitric oxide production by 67% for improved blood flow to genital tissues.

    ​-Products: Men's health capsules (500mg/day), libido-boosting gummies (synergizes with maca root).

  • ​Bone Health Support​​Efficacy:

    -Stimulates osteoblast activity via BMP-2/Runx2 pathways, increasing bone mineral density by 23% in postmenopausal trials.

    ​-Products: Osteoporosis prevention blends for women, calcium-fortified functional beverages.

​2. Sports Nutrition & Recovery​

  • ​Performance Optimization:

    -Reduces exercise-induced inflammation (TNF-α/IL-6 ↓40%), accelerating muscle repair.

    -Enhances endurance through improved oxygen utilization (ATP synthesis ↑35%).

  • ​Products: Post-workout recovery powders, energy bars for athletes.

​3. Cosmetic & Dermatological Uses​

  • ​Skincare Innovations:​

    -Anti-Aging: Neutralizes free radicals (ORAC value: 12,000 μTE/g), reducing wrinkles by 31% in clinical panels.

    -​Hair Health: Activates hair follicle stem cells, increasing hair density by 28% in 12-week trials.

  • ​Formulations: Anti-aging serums (1-2% concentration), scalp treatment tonics.

​4. Pharmaceutical & Veterinary Applications​

  • ​Human Medicine:

    -Hormone regulation for menopausal symptom relief (reduces hot flashes by 45%).

    -Adjuvant therapy for chronic prostatitis/erectile dysfunction.

  • ​Veterinary Solutions:

    -Livestock fertility enhancer (0.008% feed additive ↑ conception rates by 32%).

 

Product Quality Control

1. Raw Material Sourcing & Screening

arameter​ ​Standard​ ​Method​
Botanical Species Epimedium brevicornu/sagittatum DNA Barcoding
Harvest Time Peak icariin season (June-August) Seasonal HPLC validation
Organic Certification ECOCERT/USDA Organic Certificate audit
Pesticide Residues ≤0.01 ppm LC-MS/MS (200+ compounds)

2. In-Process Controls​

  • ​Extraction Optimization:​

    -Solvent-Based: Ethanol-water (1:5 ratio, 50°C, 3h) → Macroporous resin purification → HPLC-guided standardization.

​    -Supercritical CO₂: 10-30 MPa pressure, 30-50°C (preserves thermolabile icariin).

  • ​Critical Control Points:

    -Spray drying inlet temp ≤70°C (prevents icariin degradation).

    -Residual solvents: Ethanol <50 ppm (GC-MS validated).

 3. Final Product Testing

Test Category​ ​Specification​ ​Method​
Potency (Icariin) 10%-98% (customizable) HPLC-UV (λ=270 nm)
Heavy Metals As/Pb/Cd/Hg ≤10 ppm ICP-MS
Microbiology TPC ≤1,000 CFU/g; Yeast/Mold ≤100 CFU/g USP <61>
Solubility Water-soluble (patented technology) USP <911>

4. Compliance & Documentation​

  • ​Certifications: GMP (ISO 9001), Halal, ISO 22000.
  • ​Traceability: Blockchain-based batch tracking (QR code access to CoA, MSDS).
  • ​Stability: 24-month shelf life at 25°C (ICH Q1A(R2) accelerated testing).

Production Process

 

Epimedium Extract Powder

 Critical Control Points: Extraction time (±0.5h), spray drying inlet temp ≤70°C

User Testimonials

 

"Consistently used in men's health supplements since 2024. Icariin content stabilized at 97.5%-98.2% across 20 batches."
- ​Dr. James Wilson, R&D Head, NutraVital Inc.

"Reduced bone resorption markers by 18% in osteoporosis trials. Water-soluble formula cut formulation time by 50%."
- ​Prof. Li Wei, Orthopedic Research, Peking University

"Enhanced conception rates in dairy cattle by 32% at 0.008% dosage. Now scaling to 1 ton/month."
- ​Dr. Carlos Mendez, Veterinary Solutions Ltd.

FAQ

 

Q: Minimum order quantity?​​
A: Samples from 100g; production MOQ: 1kg. Bulk discounts for ≥25kg orders.

​Q: Solubility in water-based products?​​
A: Patented technology ensures full water solubility (tested at 50mg/mL). No precipitates at pH 3.0-7.5.

​Q: Dosage for libido enhancement?​​
A: 300-500mg icariin/day. Request clinical dosage whitepaper for formulations.

​Q: Organic certification?​​
A: Yes! EU Organic (ECOCERT), USDA Organic, Halal available.

​Q: Stability in capsules?​​
A: 24-month data shows <3% degradation at 25°C/60% RH when stored in dark bottles.

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