Spermidine Trihydrochloride Powder

Spermidine Trihydrochloride Powder

Product Name:Bulk Spermidine Trihydrochloride Powder (Spermidine 3HCl)
OEM Packaging Available
No Irradiation, Non-GMO, Non-Allergen
Min Order: 1Kg
Storage: Store in tightly closed original container, protected from light
Package: 1Kg/Aluminum foil bag or Custom Required
Inventory: 50Kg ~1000Kg
Send Inquiry
Chat Now

Bulk Spermidine Trihydrochloride Powder (Spermidine 3HCl)

Ultra-Pure Cellular Autophagy Activator · Pure Synthetic & Enzymatic Grade · Premium Crystalline Powder for Longevity Supplements

Purity ≥ 98.0% (HPLC) Trihydrochloride Form (High Stability) Ultra-Low Solvent Residuals 100% Water Soluble

R&D Insights: Free Base Spermidine vs. Spermidine Trihydrochloride

Why formulation experts strongly prefer Spermidine 3HCl for encapsulated products.

If you have ever attempted to formulate anti-aging supplements with botanical wheat germ extracts or free-base spermidine, you likely encountered two major industry pain points: extremely low active content (often less than 1%) and extreme hygroscopicity leading to powder caking during capsule filling.

Free-base spermidine is unstable and rapidly oxidizes when exposed to ambient humidity. By converting pure spermidine into its trihydrochloride salt form (Spermidine 3HCl), we achieve an exceptional active purity of ≥ 98.0% with significantly enhanced crystalline stability. This provides formulators with precise dosage control (e.g., 5mg to 10mg active spermidine per capsule) without carrying huge amounts of inactive botanical plant matter or suffering from moisture-induced shelf degradation.

Technical Specifications

Chemical Name Spermidine Trihydrochloride / N-(3-Aminopropyl)butane-1,4-diamine trihydrochloride
CAS No. / Molecular Formula 334-50-9 / C7H19N3·3HCl (Molecular Weight: 254.63 g/mol)
Appearance & Form White to off-white crystalline powder, free-flowing
Assay (Purity) ≥ 98.0% (HPLC / Titration verified)
Solubility 100% water soluble; yields a clear, transparent solution
Loss on Drying ≤ 1.0% (Strictly vacuum dried for powder stability)
Heavy Metals & Arsenic Heavy Metals < 10 ppm | Pb < 2 ppm | As < 1 ppm | Cd < 1 ppm | Hg < 0.1 ppm
Microbial Control Total Plate Count < 1,000 cfu/g; Yeast & Mould < 100 cfu/g; E. coli / Salmonella Negative
Recommended Storage 24 Months when stored in tightly sealed containers at 2–8°C away from light and humidity

📄 Request Official Quality Documents & Test Reports (Free PDF)

Need batch-specific lab results or customs compliance files? We provide official stamped documents for your quality audit:

Standard Specs: COA | TDS | Flow Chart | MSDS / SDS
Quality & Safety: Nutrition Facts | 3rd-Party Test Report | Compliance Cert | Pesticide Residue | Residual Solvent

Request Documents Now → ⚡ Guaranteed reply within 24 hours

Why Premium Source Our Spermidine 3HCl

1. Guaranteed ≥98% Purity (HPLC)

Every batch is validated by HPLC to ensure minimal impurities. You receive concentrated active spermidine rather than diluted plant material.

2. Superior Crystalline Flowability

Engineered through controlled crystallization to ensure consistent particle size distribution. Runs smoothly through high-speed automatic encapsulation machines.

3. Ultra-Low Residual Solvents

Purified without harsh industrial solvents. Complies strictly with ICH Q3C guidelines for residual solvents, guaranteeing clean-label compliance for global markets.

4. Batch-to-Batch Consistency

Manufactured in cGMP-certified facilities under standardized synthesis protocols. Minimizes production adjustments and batch failures in your factory.

Target Applications & Formulation Ideas

Anti-Aging & Longevity Capsules

Primary active ingredient for cellular renewal, autophagy activation, and anti-senescence dietary supplements (typically dosed at 1mg–10mg per serving).

Synergistic Nootropic & NAD+ Blends

Pairs exceptionally well with NMN, NR, Resveratrol, and Pterostilbene to target multiple cellular longevity pathways simultaneously.

Hair Growth & Follicle Care Formulas

Utilized in premium hair health supplements to promote hair follicle stem cell elongation and delay anagen-to-catagen hair phase transition.

Soluble Instant Drinks & Sachets

100% water solubility allows seamless incorporation into clear functional powders and stick packs without sediment build-up.

Formulator & Industry Client Feedback

★★★★★

"We used to struggle with wheat germ extracts because the active spermidine content was too low to fit into a single capsule dose. Switching to their 98% Spermidine 3HCl allowed us to create a clean, high-potency product."

- Dr. Julian S., Chief Scientific Officer, Longevity Supplement Brand (USA)

★★★★★

"Power flowability and moisture control are critical for our high-speed encapsulation lines. Their Spermidine 3HCl batch was dry, uniform, and didn't stick to the dosing discs. Extremely satisfied."

- Mark W., Factory Production Manager, Contract Manufacturer (UK)

★★★★★

"Full analytical support is hard to come by with raw material suppliers. Their batch shipment came with NMR, HPLC chromatograms, and heavy metal testing reports that satisfied our strict EU compliance team."

- Claire B., Regulatory Affairs Lead, Nutraceuticals (France)

★★★★★

"Great communication and reliable shipping. We ordered 5 kg for our initial trial run, and the material dissolved completely clear in water without any off-odors. Will be placing our 50 kg bulk order soon."

- Hans M., Procurement Director, Health Products (Germany)

Quality System & Compliance Documentation

✓ cGMP Factory Certification

Produced in ISO22000 and cGMP-certified production lines. Non-GMO, Halal, Kosher, and Allergen-free declaration provided.

✓ Complete Analytical Dossier

Every batch includes HPLC testing chromatograms, 1H-NMR spectrum, Heavy Metal / Pesticide assays, MSDS, and Stability Data.

Packaging & Moisture-Proof Logistics

Moisture-Barrier Packaging

• Small Lot: 1 kg / Vacuum-Sealed Heavy Duty Aluminum Foil Bag with Desiccant Pack.
• Bulk Drum: 10 kg / 25 kg Fiber Drum with double food-grade PE moisture-barrier inner liners.

Global Express Shipping

• R&D Evaluation Kits: 3–5 business days via FedEx / DHL Express.
• Commercial Orders: Air Freight or Ocean Freight with temperature & moisture monitored tracking.

Frequently Asked Questions (FAQ)

Q1: What is the main advantage of Spermidine 3HCl over natural wheat germ extract?

A: Natural wheat germ extract contains only 0.1% to 1.0% active spermidine, requiring consumers to swallow multiple huge capsules daily. Spermidine 3HCl delivers ≥98% active purity, enabling formulators to offer precise, high-potency daily dosages in standard 0# or 1# hard capsules.

Q2: How should Spermidine Trihydrochloride powder be handled to prevent moisture absorption?

A: Although the trihydrochloride salt form is significantly more stable than free-base spermidine, it remains slightly hygroscopic. We recommend working in a humidity-controlled cleanroom (RH < 40%) during weighing and encapsulation, and keeping unused powder tightly sealed in vacuum foil bags.

Q3: Is your Spermidine 3HCl produced by chemical synthesis or fermentation?

A: Our material is manufactured via high-efficiency, ultra-clean chemical synthesis followed by multi-stage crystallization. This method avoids unpredictable agricultural crop contaminants, heavy metals, and gluten allergens common in wheat extracts.

Q4: Is Spermidine Trihydrochloride suitable for vegan or gluten-free products?

A: Yes, 100%. Our synthetic process uses zero animal-derived raw materials and zero grain inputs. It is certified 100% Vegan, Gluten-Free, and Non-GMO.

Q5: What is the Minimum Order Quantity (MOQ) for bulk testing?

A: Our MOQ for trial pilot testing is 1 kg in a vacuum-sealed foil bag. We also offer 10g–50g sample kits for initial lab testing and analytical qualification.

Q6: How can our technical team request a sample and COA?

A: Simply click the inquiry button below or contact our sales engineers. We will provide a complete technical package including batch-specific COA, HPLC spectra, and sample dispatch within 24 hours.

Ready to Formulate Premium Longevity Supplements?

Request complimentary 10g–50g sample kits with batch-specific COA, HPLC chromatograms, and NMR spectra.

Request Free Samples & Bulk Quotation

Hot Tags: spermidine trihydrochloride powder, China spermidine trihydrochloride powder suppliers, manufacturers, factory