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Grapefruit Seed Extract

Grapefruit Seed Extract

Botanical Source: Citrus paradise seed
CAS Number: 90045-43-5;Molecular formula: C6H8O6
Molecular weight: 176.13
Appearance: Yellow brown powder
Odor: characteristic
Specification: Bioflavonoids >50% By HPLC GSE 10:1 20:1

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Product Details

Basic Information
Botanical SourceCitrus paradise seedCAS Number90045-43-5
Molecular formulaC6H8O6Molecular weight176.13
AppearanceYellow brown powderOdorcharacteristic
SpecificationBioflavonoids >50% By HPLC   GSE 10:1  20:1

Product Introduction
Grapefruit extract Naringin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of selected drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions in vivo.

Ingestion of Grapefruit extract Naringin and related flavonoids can also affect the intestinal absorption of certain drugs, leading to either an increase or decrease in circulating drug levels. To avoid interference with drug absorption and metabolism, the consumption of citrus (esp. Grapefruit) and other juices with medications is contraindicated.
Grapefruit extract Naringin, citrus naringin, followed by rutin, was the most potent flavonoid inhibitor of VEGF release, which causes angiogenesis, out of 21 flavonoids. When grapefruit extract naringin is treated with potassium hydroxide or another strong base, and then catalytically hydrogenated, it becomes a naringin dihydrochalcone, a compound roughly 300-1800 times sweeter than sugar at threshold concentrations.
Studies have shown that citrus naringin interferes with enzymatic activity in the intestines and, thus, with the breakdown of certain drugs, resulting in higher blood levels of the drug. A number of drugs that are known to be affected by the naringin in grapefruit include calcium channel blockers, estrogen, sedatives, medications for high blood pressure, allergies, AIDS, and cholesterol-lowering drugs.

Main Function
• Be used externally as a disinfectant for both intact skin and to prevent infection in wounds;

• Treat hundreds of adverse health conditions in humans and animals alike.

• Naringin has anti-inflammatory analgesic, anti-viral, antibacterial and aldose reductase inhibitory effect of the eye.



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