Products Description
GHK-Cu Powder 99% Pure - Pharmaceutical Grade Copper Tripeptide Complex | Skin Regeneration & Anti-Aging
Our GHK-Cu Powder is a high-purity copper peptide complex (glycyl-histidyl-lysine-copper) synthesized through advanced peptide engineering techniques. Standardized to 99% purity, this off-white to light blue crystalline powder is a naturally occurring tripeptide that plays a critical role in skin regeneration, wound healing, and anti-aging processes.
Produced using solid-phase peptide synthesis (SPPS) under GMP conditions, our GHK-Cu maintains exceptional bioactivity and stability. This copper complex mimics the body's natural regenerative peptides, supporting collagen production, reducing inflammation, and promoting healthy tissue formation.
Free from contaminants, solvents, and heavy metals, our GHK-Cu Powder meets stringent pharmaceutical and cosmetic standards, including USP, EP, and ISO guidelines. It integrates seamlessly into topical formulations, serums, and research applications, delivering consistent results in both clinical and cosmetic settings.
Product Specifications
| Parameter | Specification | Testing Method | Compliance Standard |
|---|---|---|---|
| Chemical Name | Glycyl-L-histidyl-L-lysine copper (II) complex | NMR, Mass Spectrometry | IUPAC Nomenclature |
| Assay (GHK-Cu) | ≥99.0% | RP-HPLC (C18 Column) | USP 43, EP 9.0 |
| Appearance | Blue powder/blue transparent liquid | Visual Inspection | Pharmaceutical Standards |
| Molecular Weight | 497.9 g/mol | Mass Spectrometry | Analytical Standards |
| Solubility | Soluble in water (≥10 mg/ml) | Solubility Test | USP <1236> |
| Loss on Drying | ≤0.5% | USP <731> (105°C, 2 hours) | USP, EP |
| Residue on Ignition | ≤0.1% | USP <281> | USP, EP |
| Heavy Metals | Total ≤5ppm (Pb ≤1ppm, Cd ≤0.1ppm, Hg ≤0.01ppm, As ≤0.1ppm) | ICP-MS | ICH Q3D |
| Copper Content | 14.0-16.0% | Atomic Absorption | USP <231> |
| Peptide Related Substances | Single impurity ≤0.5%, Total impurities ≤1.0% | HPLC | EP 2.2.25 |
| Residual Solvents | Acetonitrile ≤410ppm, Dichloromethane ≤600ppm | GC-FID | ICH Q3C |
| Microbial Contamination | Total Aerobic Count ≤100 cfu/g, Yeast/Mold ≤10 cfu/g, Pathogens: Negative | USP <61>/<62> | ISO 11930 |
| Endotoxin Content | ≤0.1 EU/mg | LAL Assay | USP <85> |
| pH (1% Solution) | 5.0-7.0 | pH Meter | EP 2.2.3 |
| Certifications | GMP, ISO 22716, FDA-registered facility, REACH compliant | Third-Party Audits | Global Pharmaceutical & Cosmetic Standards |
Product advantages
Why Choose Our GHK-Cu Powder
GHK-Cu Powder 99% Pure - Pharmaceutical Grade Copper Tripeptide Complex
Ultra-High Purity
99% minimum purity ensures maximum bioactivity and minimal impurities in sensitive applications.
Pharmaceutical Grade
Manufactured in a GMP-certified facility using USP-grade raw materials, meeting the highest safety standards.
Optimal Bioactivity
Precision-engineered copper complexation preserves the natural regenerative properties of GHK peptide.
Exceptional Stability
Enhanced stability in aqueous formulations compared to uncomplexed GHK, with 24-month shelf life under proper storage.
Consistent Performance
Batch-to-batch uniformity with tight specification controls, critical for formulation consistency.
Versatile Solubility
Easily soluble in water (≥10mg/ml) for simple integration into various cosmetic and pharmaceutical formulations.
Product Applications
Our GHK-Cu Powder offers versatile applications across cosmetic, pharmaceutical, and research industries:
1 Cosmeceuticals & Skincare
- Anti-Aging Formulations: GHK-Cu stimulates collagen and elastin production, reducing the appearance of fine lines and wrinkles. It enhances skin firmness and elasticity when included in serums at 0.01-0.1% concentrations.
- Wound Healing Products: Accelerates skin repair in formulations for post-procedure care, supporting faster recovery from chemical peels, microdermabrasion, and laser treatments.
- Anti-Inflammatory Serums: Reduces redness and inflammation in sensitive skin formulations, making it suitable for rosacea and acne-prone skin products.
- Brightening Formulations: Inhibits melanin production, helping to reduce hyperpigmentation and improve overall skin tone uniformity.
- Hair Care Products: Promotes hair follicle health and reduces hair loss when included in topical treatments and shampoos.
2 Pharmaceutical Applications
- Dermatological Medications: Used in prescription formulations for treating chronic wounds, burns, and ulcerations due to its tissue regenerative properties.
- Anti-Scarring Treatments: Reduces scar formation by promoting normal collagen synthesis and preventing excessive scar tissue buildup.
- Ophthalmic Formulations: Research indicates potential benefits in treating eye conditions through its anti-inflammatory and tissue-repair properties.
- Oral Care Products: Added to advanced toothpastes and mouthwashes for gum health and tissue regeneration in periodontal applications.
3 Research & Biotechnology
- Tissue Engineering: Valuable in laboratory studies on skin regeneration, cartilage repair, and bone tissue engineering.
- Cell Culture Research: Used to study cell migration, proliferation, and differentiation in various cell lines.
- Biomedical Research: Investigated for potential applications in regenerative medicine, including stem cell research and tissue repair mechanisms.
- Cosmetic Science: Serves as a reference standard in developing new anti-aging and skin-repair formulations.
4 Veterinary Applications
- Animal Wound Care: Used in veterinary formulations for treating wounds, burns, and skin conditions in companion animals.
- Equine Products: Included in topical treatments for horses to promote healing of skin injuries and ulcers.
Company Advantages
Advanced Manufacturing
Utilizes state-of-the-art solid-phase peptide synthesis (SPPS) technology with automated purification systems, ensuring 99% purity consistently.
Quality Infrastructure
Produced in an FDA-registered, GMP-certified facility compliant with ISO 22716 (cosmetics) and ISO 13485 (medical devices), ensuring product safety and consistency.
Rigorous Quality Control
In-house ISO 17025-accredited laboratory performs 40+ quality tests per batch, including peptide mapping, impurity profiling, and bioactivity verification.
Production Capacity
Flexible manufacturing from small research quantities (1g) to commercial-scale production (50kg/month) with 10-day turnaround for standard orders.
Regulatory Support
Comprehensive documentation packages including DMF assistance, stability data, and safety assessments to support customer regulatory submissions.
ormulation Expertise
In-house technical team provides formulation support, helping customers optimize GHK-Cu integration into their specific products.
Product Case Studies
Product Success Cases
GHK-Cu Powder 99% Pure - Pharmaceutical Grade Copper Tripeptide Complex
Case 1: Luxury Skincare Brand
Challenge: A high-end skincare company needed a stable, high-purity GHK-Cu for their anti-aging serum line, requiring consistent performance, clinical efficacy data, and compliance with EU cosmetic regulations.
Solution: We provided 99% pure GHK-Cu with comprehensive stability data in aqueous formulations. Our technical team assisted with dosage optimization (0.05% concentration) and compatibility testing with their existing ingredients.
Result: The serum line achieved a 42% increase in sales, with clinical trials showing 87% of users experienced improved skin firmness after 8 weeks. Our GHK-Cu's stability eliminated previous formulation degradation issues, extending product shelf life from 6 to 18 months. They now place monthly orders of 5kg.
Case 2: Pharmaceutical Research Company
Challenge: A biotech firm researching wound-healing therapies required ultra-pure GHK-Cu with full impurity profiles and endotoxin testing for their pre-clinical studies.
Solution: We supplied GHK-Cu with 99.5% purity, complete peptide mapping, and endotoxin levels <0.05 EU/mg. We also provided custom packaging in 1g aliquots for their animal studies and assisted with material safety data for regulatory submissions.
Result: The company successfully demonstrated accelerated wound closure in their murine model, with their research published in a leading dermatology journal. They've expanded their studies to human trials and now order 10kg quarterly, with our GHK-Cu specified as the reference material.
Case 3: Cosmetic Contract Manufacturer
Challenge: A large contract manufacturer needed a reliable GHK-Cu supplier for multiple client formulations, requiring consistent quality, competitive pricing, and flexible delivery schedules.
Solution: We established a dedicated production schedule with bulk pricing tiers, providing 25kg monthly with the ability to scale up to 50kg within 2 weeks. We also supplied customized documentation packages tailored to each client's regional regulatory requirements.
Result: The manufacturer reduced their raw material costs by 15% while improving formulation consistency across their product lines. They've expanded their GHK-Cu-containing products from 3 to 12 formulations, with our material becoming their sole source for copper peptides.
Packaging & Shipping
Packaging Options
| Order Size | Packaging Type | Material Standards | Shelf Life |
|---|---|---|---|
| Research Quantities (1g–10g) | Amber glass vials with Teflon-lined caps | USP Type I Glass | 24 months (proper storage) |
| Small Batch (50g–100g) | Vacuum-sealed foil pouches in moisture-barrier containers | FDA 21 CFR Part 177 | 24 months |
| Medium Batch (500g–1kg) | Aluminum cans with nitrogen flush | ISO 15378 | 24 months |
| Bulk (5kg–50kg+) | Stainless steel drums with double PE liners | USP Pharmaceutical Standards | 24 months |
| Custom Orders | Client-specified packaging (including private labeling) | Client requirements | 24 months |
All packaging includes batch number, COA reference, production date, expiry date, QR code for full traceability, and storage instructions: "Store at -20°C to -8°C in tightly closed container; protect from light and moisture. Avoid repeated freeze-thaw cycles."
Shipping Information
- Transport Modes:
- Express (DHL/FedEx): 2–4 days (all quantities, with dry ice)
- Air Freight: 5–7 days (bulk orders, temperature-controlled)
- Cold Chain Logistics: For large orders requiring maintaining -20°C temperature
- Storage Conditions: Shipped with dry ice (for orders <5kg) or in cryogenic containers (for larger orders) to maintain stability during transport.
- Documentation: Each shipment includes comprehensive documentation:
- Certificate of Analysis (COA) with full impurity profile and HPLC chromatogram
- Material Safety Data Sheet (MSDS/SDS)
- Certificate of Origin and Free Sale Certificate
- Stability Data (real-time and accelerated)
- Regulatory compliance documentation for target markets
- Handling and storage instructions
- Customs Compliance: Pre-prepared documents for cosmetic and pharmaceutical imports, including cosmetic product notifications (CPNP) for EU markets and FDA import documentation for US.
Customer Reviews
User Evaluation
Elena M.
R&D Director
Dr. Robert K.
Principal Researcher
Michael T.
Procurement Manager
FAQ
Everything You Need to Know
GHK-Cu Powder 99% Pure - Pharmaceutical Grade Copper Tripeptide Complex
What is GHK-Cu Powder?
GHK-Cu Powder is a high-purity copper peptide complex consisting of the tripeptide glycyl-histidyl-lysine bound to copper (II) ions. It's known for its skin regenerative, anti-aging, and wound-healing properties.
What is the purity of your GHK-Cu Powder?
Our GHK-Cu Powder is standardized to 99% minimum purity, verified by HPLC analysis, making it suitable for pharmaceutical, cosmetic, and research applications.
How is GHK-Cu used in skincare?
GHK-Cu is incorporated into serums, creams, and treatments at concentrations of 0.01-0.1% to improve skin elasticity, reduce wrinkles, enhance wound healing, and promote overall skin health.
How is GHK-Cu produced?
Our GHK-Cu is produced using solid-phase peptide synthesis (SPPS) to create the GHK tripeptide, followed by controlled copper complexation, HPLC purification, and lyophilization to produce a stable powder.
What are the main benefits of GHK-Cu?
GHK-Cu supports collagen production, accelerates wound healing, reduces inflammation, improves skin firmness, and has antioxidant properties, making it valuable in anti-aging and regenerative formulations.
What are the storage requirements for GHK-Cu Powder?
GHK-Cu Powder should be stored at -20°C to -8°C in a tightly closed container, protected from light and moisture. When stored properly, it maintains stability for 24 months.
Is your GHK-Cu suitable for pharmaceutical applications?
Yes, our GHK-Cu Powder is produced in a GMP-certified facility, meets pharmaceutical standards (USP, EP), and is suitable for dermatological medications and wound-healing formulations.
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