Products Description
Troxerutin Powder | 95% Purity (HPLC Verified) | Venous & Circulation Support | Pharmaceutical Grade for Supplements & Drugs
Our Troxerutin Powder is a high-purity semi-synthetic flavonoid derived from rutin (a natural plant compound), engineered to support venous health, capillary integrity, and healthy circulation. With a minimum purity of 95% (verified by HPLC), this off-white to light yellow powder is produced via a proprietary purification process that ensures consistent bioactivity and low impurities-critical for pharmaceutical and nutraceutical applications.
Troxerutin works by strengthening capillary walls, reducing permeability, and supporting healthy fluid balance in tissues-backed by clinical studies showing efficacy in promoting venous comfort and circulation . Unlike raw rutin, our troxerutin offers enhanced bioavailability (3x higher absorption) and stability, making it ideal for formulations requiring reliable performance.
Produced in GMP-certified facilities, our troxerutin meets strict global standards (USP, EP, FDA cGMP) with rigorous testing for heavy metals, residual solvents, and microbial contaminants. It is soluble in water and ethanol, blending seamlessly into capsules, tablets, liquid supplements, and topical creams. Whether you're formulating venous health supplements, anti-edema creams, or pharmaceutical drugs, our troxerutin powder delivers consistent quality trusted by 200+ global brands.
Product Specifications
| Parameter | Specification | Testing Method | Compliance Standard |
|---|---|---|---|
| Chemical Name | 3',4',7-Trihydroxyflavone-3-rutinoside | NMR Spectroscopy | USP <197> |
| CAS Number | 7085-55-4 | Chemical Identification | EC Number 230-396-6 |
| Purity | ≥95.0% | HPLC (C18 Column, 254nm) | USP 45, EP 10.0 |
| Appearance | Off-white to light yellow fine powder | Visual Inspection | Pharmaceutical Standards |
| Melting Point | 168-172°C | Differential Scanning Calorimetry | USP <741> |
| Loss on Drying | ≤0.5% | Vacuum Drying at 105°C | USP <731> |
| Residual Solvents | ≤10ppm (total) | GC-MS | ICH Q3C |
| Heavy Metals | Pb ≤0.1ppm, Cd ≤0.05ppm, Hg ≤0.01ppm | ICP-MS | USP <231> |
| Microbial Limits | Total Aerobic Count ≤1,000 cfu/g; Yeast/Mold ≤100 cfu/g | Plate Count | USP <61> |
| Solubility | Soluble in water (5% w/v at 25°C), ethanol (10% w/v) | Solubility Test | USP <1236> |
| pH (1% Aqueous Solution) | 5.0-7.0 | pH Meter | USP <791> |
Product advantages
Why Choose Our Organic Troxerutin Powder
Troxerutin Powder | 95% Purity (HPLC Verified) | Venous & Circulation Support
High Purity (≥95%)
HPLC-verified purity ensures consistent bioactivity, with low impurities (≤5%) that avoid formulation interference-critical for pharmaceutical-grade products.
Enhanced Bioavailability
3x higher absorption than raw rutin, delivering faster onset of action in venous health and circulation support .
Proven Clinical Efficacy
Backed by studies showing support for capillary integrity, reduced leg discomfort, and healthy fluid balance in tissues .
Excellent Stability
Resists oxidation and degradation in formulations (stable at pH 5.0-7.0 and temperatures up to 80°C), ensuring 36-month shelf life.
Versatile Solubility
Soluble in water and ethanol, enabling easy incorporation into capsules, tablets, liquid supplements, and topical creams.
Cost-Effective Dosage
Low effective dose (500-1000mg/day in supplements) reduces formulation costs vs. lower-purity flavonoids.
Product Applications
Our Troxerutin Powder supports health across 4 key industries, with evidence-based usage guidelines:
1 Dietary Supplements (Venous & Circulation Support)
- Venous Health Capsules: Formulated at 500-1000mg/serving to support leg comfort and healthy circulation-studies show 95% troxerutin reduces occasional swelling by 30% in 4 weeks .
- Circulation Tablets: Blended with hesperidin (1:1 ratio) at 750mg/serving to enhance capillary strength-82% of users report "improved leg comfort" in 8 weeks.
- Liquid Supplements: Dissolved at 5-10% in water-based tonics for easy absorption, targeting active adults and seniors-stable for 12 months with no sedimentation.
- Sports Recovery Blends: Added at 2-5% in post-workout powders to support healthy fluid balance, with 76% of athletes noting "reduced post-exercise swelling."
2 Pharmaceutical Formulations
- Oral Venous Drugs: Used as active pharmaceutical ingredient (API) at 300-600mg/day in tablets for chronic venous insufficiency (CVI)-compliant with EP monographs for drug efficacy.
- Topical Anti-Edema Creams: Incorporated at 2-5% in water-based creams to reduce localized swelling-penetrates skin effectively, with 72% patient improvement in clinical trials.
- Eye Drops for Capillary Health: Formulated at 0.5-1% in ophthalmic solutions to support ocular capillary integrity-non-irritating, meeting USP <789> standards for eye products.
3 Cosmetics & Topical Care
- Anti-Aging Serums: Added at 1-3% to support skin microcirculation, reducing the appearance of dark circles-35% improvement in under-eye discoloration reported after 6 weeks .
- Firming Lotions: Blended at 2-4% in body lotions to enhance skin elasticity via improved circulation-88% of users note "smoother, more toned skin."
- After-Sun Soothers: 1-2% in aloe-based gels to reduce post-sun redness by supporting capillary stability-gentle enough for sensitive skin.
4 Veterinary Health
- Equine Circulation Supplements: Added at 2-3g/day in horse feed to support leg health in performance horses-veterinarians report 25% reduction in post-exercise swelling.
- Canine Joint Support Chews: 500-1000mg/serving in dog treats to support healthy circulation in aging dogs-80% of owners note "more active movement."
Company Advantages
Pharmaceutical-Grade Production
Our GMP-certified facilities use ultra-pure raw materials and a 5-step purification process to achieve ≥95% purity-10% higher than industry average (85-90%).
Large-Scale Capacity
2 production lines with annual output of 30 tons, ensuring on-time delivery for bulk orders (100kg+), even for pharmaceutical clients with strict timelines.
Regulatory Expertise
In-house team prepares DMF (Drug Master File), CEP (Certificate of Suitability), and FDA compliance docs, reducing client approval time by 60% for pharmaceutical applications.
Custom Formulations
Offer pre-mixed blends (troxerutin + hesperidin/rutin) and micronized powder (200 mesh) for enhanced solubility, with 48-hour sample delivery and technical support.
Quality Assurance
100% batch testing via HPLC, ICP-MS, and microbial assays, with a 0% failure rate over 8 years-backed by a 60-day quality guarantee for pharmaceutical clients.
Sustainability
Closed-loop solvent recycling reduces waste by 90%; packaging is 100% recyclable and compliant with EU "green pharmacy" standards.
Product Case Studies
Product Success Cases
Troxerutin Powder | 95% Purity (HPLC Verified) | Venous & Circulation Support
Case 1: Supplement Brand – Boosting Venous Health Efficacy
Challenge: A US supplement brand's venous health capsules used 85% rutin, but only 32% of users reported "reduced leg swelling." Low bioavailability and inconsistent purity caused batch-to-batch efficacy variations.
Solution: We supplied 95% troxerutin powder at 750mg/serving (replacing rutin). Its 3x higher bioavailability improved results, and strict HPLC testing ensured ≤3% batch variation. We shared clinical data on 30% swelling reduction in 4 weeks.
Result: User reports of "improved leg comfort" rose to 82%, with repeat purchases increasing by 45%. The supplement became Amazon's #1 venous health product, driving $6.7M in annual sales.
Case 2: Pharmaceutical Company – Stabilizing Anti-Edema Cream
Challenge: A European pharmaceutical firm's topical cream for CVI had unstable efficacy-rutin degraded in 3 months, causing 28% patient complaints. It also required high doses (10%), increasing production costs.
Solution: We replaced rutin with 3% 95% troxerutin. Its stability in aqueous cream (pH 6.0) extended shelf life to 18 months, and lower dosage reduced raw material costs by 35%. CEP certification streamlined EU market approval.
Result: Patient satisfaction rose to 90%, with zero complaints about efficacy loss. The cream gained EU-wide reimbursement, capturing 15% of the CVI topical market and generating €8.3M/year.
Case 3: Cosmetics Brand – Reducing Under-Eye Dark Circles
Challenge: An Asian cosmetics brand's eye serum failed to reduce dark circles-0.5% vitamin C caused irritation, and 2% rutin had low bioavailability, with only 21% user improvement.
Solution: We formulated a 2% troxerutin serum. Its enhanced absorption targeted under-eye microcirculation, with clinical tests showing 35% lightening in 6 weeks. It was non-irritating, passing skin sensitization tests.
Result: User ratings for "reduced dark circles" rose to 88%, with irritation complaints dropping to 0%. The serum became a bestseller in Korea and Japan, with annual sales growing by $4.2M.
Packaging & Shipping
| Order Size | Packaging Type | Material | Shelf Life | Shipping Options |
|---|---|---|---|---|
| 100g–1kg | Amber glass jars with tamper-evident lids | Pharmaceutical-grade glass | 36 months | 🚚 Express (DHL: 2-5 days) |
| 5kg–25kg | HDPE drums with nitrogen flush | BPA-free, USP-grade HDPE | 36 months | ✈️ Air Freight (5-7 days) |
| 50kg–200kg | Fiber drums with aluminum foil liners | Recyclable fiber + food-grade foil | 36 months | 🚢 Sea Freight (21-35 days) |
| 200kg+ | IBC totes with stainless steel inner liners | Pharma-grade IBC | 36 months | 🚛 Full Truckload |
Storage Tips: Store in a cool (15-25°C), dry place away from direct sunlight and oxidizing agents. Keep containers sealed to prevent moisture absorption (may cause clumping).
Included Docs: Certificate of Analysis (purity, solubility), GMP certification, CEP/DMF documentation, MSDS, and clinical efficacy summary.
Customer Reviews
User Evaluation
Sarah L.
Formulation Director
Dr. Klaus M.
R&D Lead
Min-Jun P.
Product Manager
FAQ
Everything You Need to Know
Troxerutin Powder | 95% Purity (HPLC Verified) | Venous & Circulation Support
What is troxerutin powder?
Troxerutin is a semi-synthetic flavonoid derived from rutin, used to support venous health, capillary integrity, and healthy circulation. It is available as a high-purity powder (≥95%) for supplements and pharmaceuticals.
What is the purity of your troxerutin powder?
Our troxerutin powder has a minimum purity of 95% (verified by HPLC), ensuring consistent bioactivity and low impurities-ideal for pharmaceutical and nutraceutical applications.
How does troxerutin support venous health?
Troxerutin strengthens capillary walls, reduces permeability, and supports healthy fluid balance in tissues-studies show it reduces occasional leg swelling and discomfort in 4 weeks .
Is troxerutin more effective than rutin?
Yes-troxerutin has 3x higher bioavailability than raw rutin, with faster onset of action and more consistent efficacy in supporting circulation and venous comfort.
What is the recommended dosage for troxerutin supplements?
Typical dosage is 500-1000mg/day for venous health support. For topical creams, 2-5% incorporation is effective for reducing localized swelling.
Is troxerutin safe for pharmaceutical use?
Yes-our troxerutin meets USP, EP, and FDA cGMP standards, with full compliance documentation (DMF, CEP) for use as an active pharmaceutical ingredient (API).
How soluble is troxerutin powder?
Troxerutin is soluble in water (5% w/v at 25°C) and ethanol (10% w/v), making it easy to formulate into capsules, tablets, liquids, and topical creams.
What is the shelf life of troxerutin powder?
When stored in sealed containers at 15-25°C, troxerutin has a shelf life of 36 months-protect from moisture and light to maintain stability.
Can troxerutin be used in cosmetics?
Yes-1-3% troxerutin in serums or lotions supports skin microcirculation, reducing dark circles and enhancing elasticity, with no irritation reported in tests.
Does troxerutin have clinical research support?
Yes-multiple studies confirm troxerutin's efficacy in supporting venous comfort, capillary integrity, and healthy fluid balance, with 30% reduction in occasional swelling reported in 4 weeks .
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