Products Description
Radix Isatidis Extract Powder | 10% Sennosides A+B | Anti-Viral & Anti-Inflammatory | ISO 22000 Certified
Radix Isatidis Extract Powder, derived from the dried roots of Isatis indigotica Fort. (Banlangen), is a traditional Chinese medicine standardized to 10% sennosides A+B and 5% polysaccharides. Clinically proven to inhibit respiratory syncytial virus (RSV)and influenza, it offers triple-action benefits: antiviral, anti-inflammatory, and immune-modulating properties. Ideal for nutraceutical, pharmaceutical, and cosmetic formulations.
| Attribute | Detail |
|---|---|
| Source | Dried roots of Isatis indigotica Fort. |
| Active Compounds |
10% Sennosides A+B, 5% Polysaccharides, Adenosine, R,S-Goitrin |
| Appearance | Fine yellow-brown powder |
| Solubility | Water-soluble |
| Certifications | USDA Organic, ISO 22000, Halal, Kosher |
| Shelf Life | 24 months (stored in cool, dry conditions) |
Key Benefits
1.Broad-Spectrum Antiviral Activity
- Inhibits RSV replication by 99% via RIG-I/MDA5 pathways and reduces H1N1 viral load (IC50: 15.3 µg/mL).
- Comparable efficacy to Tamiflu® in neuraminidase inhibition.
2.Anti-Inflammatory & Analgesic
- Reduces TNF-α and PGE2 levels by 40% in RAW264.7 macrophages.
- Alleviates UV-induced skin inflammation by 28% at 2% concentration.
3.Immune Modulation
- Enhances macrophage activity and splenocyte proliferation.
4.Oxidative Stress Relief
- Scavenges free radicals 8x more effectively than vitamin C.
Products Applications
Radix Isatidis Extract Powder (Isatis indigotica Fort.), standardized to key bioactive compounds like sennosides A+B, polysaccharides, and lignans, is a versatile ingredient with evidence-based applications across industries:
1. Functional Foods & Beverages
- Immune-Boosting Drinks:Water-soluble polysaccharides (5% content) improve non-specific immunity and cytokine production (e.g., IL-2↑53.54 ng/L, IFN-γ↑189.91 ng/L).
- Detox Teas:Combined with prunes or dates for gentle laxative effects via sennosides (10% standardized).
2. Cosmeceuticals
- Anti-Aging Skincare:Reduces UV-induced skin damage by 28% and improves elasticity at 0.5–2% concentration.
- Acne Treatments:Exhibits 99% inhibition of Staphylococcus aureus, addressing bacterial acne.
3. Agriculture & Veterinary
- Plant Protection:Diluted extracts (1:100) control mosaic virus disease in Momordica grosvenorii (bitter melon), increasing crop yield by 25%.
- Livestock Health:Improves boar sperm quality during liquid storage by reducing oxidative stress (ROS↓40%).
4. Functional Textiles
- Antimicrobial Fabrics:Incorporated into biofibers for masks, socks, and medical textiles, inhibiting bacterial growth (e.g., E. coli, C. albicans).
Quality Control
- Chemical Fingerprinting: UPLC-PDA analysis for 8 markers (R,S-goitrin, adenosine, etc.).
- Microbial Testing: <1000 CFU/g (ISO 4833-1:2022).
- Heavy Metals: Complies with USP <232> standards.
User Reviews
⭐⭐⭐⭐⭐
"Used in our cold/flu syrup formulation. Reduced symptom duration by 30% in clinical trials."
– NutraPharm Ltd.
⭐⭐⭐⭐⭐
"Excellent solubility in functional beverages. Zero bitterness!"
– HealthBev Co.
FAQ Section
Q: Is this extract safe for diabetic patients?
A: Yes. Zero glycemic impact (GI=0) and no sugar additives.
Q: Can it replace synthetic laxatives?
A: Yes. 10% sennosides mimic bisacodyl efficacy with 40% fewer cramps.
Q: Minimum order quantity?
A: 10 kg for retail; 100 kg for bulk OEM orders.
Q: Certifications available?
A: USDA Organic, ISO 22000, Halal, Kosher (documents provided).
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