Standardized Lemon Balm Extract Powder (Melissa officinalis L. · Rosmarinic Acid 5% – 20% HPLC)
Bio-Active GABA-Transaminase Inhibitor · Cold-Water Soluble Beverage Grade & High-Density Encapsulation Powder for Stress Relief, Sleep & Nootropics
R&D Insights: Preserving Thermolabile Rosmarinic Acid & Stopping Hygroscopic Caking
Technical notes from our polyphenol extraction & beverage application engineering team.
Lemon Balm (Melissa officinalis L.) has become a flagship botanical in modern stress-relief, sleep-architecture, and calm-focus nootropics-primarily driven by its ability to inhibit GABA-transaminase (GABA-T) and boost endogenous brain GABA levels. However, anyone who has formulated with bulk Lemon Balm extract knows two common supply headaches: first, conventional high-heat drying oxidizes up to 35% of delicate Rosmarinic Acid and strips away the signature fresh citrus-mint terpene notes; second, high residual plant sugars make standard extracts intensely hygroscopic, turning drums into solid bricks during humid summer runs.
Our extraction facility solves both issues using low-temperature counter-current extraction (≤ 55°C), selective membrane ultrafiltration, and vacuum belt/low-temp spray drying. By removing excess hygroscopic mucilage and pectins while concentrating polyphenolic acids, we achieve > 94% Rosmarinic Acid retention, bulk density of 0.45–0.60 g/mL, and rapid 100% clear aqueous solubility-giving R&D teams a trouble-free raw material for capsules, gummies, and functional relaxation beverages.
Technical Specifications
| Product Name & CAS Numbers | Lemon Balm Extract Powder | Botanical CAS: 84082-61-1 | Rosmarinic Acid CAS: 20283-92-5 |
| Botanical Source & Part Used | 100% Non-GMO Melissa officinalis L. (Dried Aerial Leaves - Harvested Pre-Flowering for Peak Polyphenols) |
| Standardized Assay Grades | HPLC Standardized: Rosmarinic Acid 5.0%, 7.0%, 10.0%, 15.0% & 20.0% Total Hydroxycinnamic Acids: ≥ 15.0% (Ph. Eur. Method) | Ratio Extracts: 10:1, 20:1 |
| Appearance, Mesh & Bulk Density | Yellow-brown to medium brown fine free-flowing powder | 100% pass 80 Mesh | Bulk Density: 0.45 – 0.60 g/mL |
| Solubility & Sensory Profile | 100% Water Soluble (Clear amber solution at 1% w/v); Clean herbaceous aroma with mild, pleasant lemon-balm notes |
| Moisture, Ash & Extraction Solvent | Loss on Drying ≤ 5.0% | Sulphated Ash ≤ 6.0% | Extraction Solvent: 100% Pure Water & Food-Grade Ethanol |
| Heavy Metals & Pesticide Residues | Total Heavy Metals < 10 ppm | Pb < 1.0 ppm | As < 1.0 ppm | Cd < 0.5 ppm | Hg < 0.1 ppm | 500+ Pesticides: EU EC 396/2005 & USP <561> Compliant |
| Microbiological Control | Total Plate Count < 1,000 cfu/g | Yeast & Mold < 100 cfu/g | E. coli, Salmonella & S. aureus: Negative/25g |
| Shelf Life & Storage Conditions | 24 Months in original unopened vacuum-sealed foil liner inside fiber drum at < 25°C and < 60% RH. |
Frequently Asked Questions (FAQ)
Q1: Why is HPLC Rosmarinic Acid standardization more reliable than UV Hydroxycinnamic Acid testing?
A: UV spectrophotometry measures total phenolic absorbance non-specifically, which can easily be skewed by general tannins or oxidized polyphenols. Our HPLC method specifically isolates and quantifies true Rosmarinic Acid-the primary bio-active driver of GABA-T inhibition-while still meeting Ph. Eur. ≥15% total hydroxycinnamic acid benchmarks.
Q2: Which specification grade should we select for Ready-to-Drink (RTD) beverages vs. capsules?
A: For RTD functional beverages, stick packs, and gummies, we recommend our 5% or 7% Rosmarinic Acid CWS grade, which dissolves crystal-clear in cold water with mild, balanced herbal notes. For capsules and tablets where space is tight, our 10% or 20% Rosmarinic Acid grade delivers full clinical potency at compact fill weights (150–300 mg).
Q3: How do you test for Pyrrolizidine Alkaloids (PAs) and Tropane Alkaloids?
A: Because wild-crafted or poorly weeded fields can introduce PA-containing weeds into herbal harvests, we audit GAP farms and test every production lot via LC-MS/MS to guarantee PAs remain strictly below the strict European Commission Regulation (EU) 2023/915 limit of 400 μg/kg.
Q4: What carrier is used in your spray-dried Lemon Balm Extract Powder?
A: Our standard 5%–10% grades use a minimal amount of Non-GMO tapioca or corn maltodextrin (typically 10%–20%) to lock in volatile aromatics and prevent caking. For strict clean-label or keto formulations, we also offer 100% carrier-free (excipient-free) high-assay 15% and 20% vacuum-dried powders.
Q5: Can we request a trial sample kit with HPLC chromatograms before placing a bulk order?
A: Yes. Submit your project details in the inquiry form below, and our team will dispatch a 100g trial sample (or multiple Rosmarinic Acid grades for side-by-side bench testing) within 24–48 hours along with complete batch COAs.
Formulate Next-Gen Calm, Sleep & Nootropic Products with Confidence
HPLC-verified Rosmarinic Acid (5%–20%), non-caking flowability, crystal-clear beverage solubility, and full EU PA/pesticide compliance. Connect with our botanical specialists today.
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