Products Description
Sourced from organic Artemisia annua leaves via solvent-free supercritical CO₂ extraction, our Artemisinin Extract Powder delivers 98%-99% purity (HPLC-verified)-clinically proven to treat drug-resistant malaria with 95% efficacy, inhibit tumor growth by 40% in vitro, and modulate immune response via T-cell regulation. As the Nobel Prize-winning compound (2015, Tu Youyou), this sesquiterpene lactone (CAS 63968-64-9) targets parasites through peroxide bridge mechanisms while suppressing pro-inflammatory cytokines (IL-6, TNF-α). Certified ISO 9001, FDA-GMP, Halal, and Kosher. Ideal for antimalarial drugs, oncology supplements, and functional foods. Shelf life: 24 months in nitrogen-flushed packaging.
Product advantages
- Ultra-High Purity (≥98%): Significantly higher than industry standard (typically 95-97%), ensuring maximum efficacy in formulations.
- Solvent-Free Extraction: Supercritical CO₂ process eliminates residual solvents, meeting pharmaceutical-grade requirements.
- Organic Sourcing: Derived from sustainably grown Artemisia annua, harvested at peak artemisinin content (before flowering).
- Stable Formulation: Crystalline structure ensures long-term stability under recommended storage conditions.
- Rigorous Testing: Each batch undergoes third-party validation via HPLC and NMR to confirm purity and structural integrity.
- Regulatory Compliance: Manufactured under cGMP conditions, compliant with FDA, EMA, and WHO standards for pharmaceuticals.
Product Specifications
| Parameter | Specification | Test Method |
|---|---|---|
| Source | Artemisia annua Leaves | HPTLC |
| Artemisinin Content | 98%-99% (Customizable: 10%-99%) | HPLC |
| Appearance | White Crystalline Powder |
Visual |
| Particle Size | 100% pass 80 mesh | USP <786> |
| Solubility | Oil-Soluble (Water-Soluble Option) | Eur.Ph. 2.9.22 |
| Heavy Metals | Pb≤0.5ppm, As≤0.3ppm, Cd≤0.1ppm | ICP-MS |
| Microbials | TPC ≤1,000 CFU/g; Pathogens Absent |
USP <61> |
| Certifications | ISO 9001, GMP, FDA-GRAS, Halal | - |
Quality Control Measures
- Raw Material Testing: Each plant batch is tested for artemisinin content (≥1.5% in raw material) and pesticides via UPLC-MS.
- In-Process Monitoring: Extraction pressure, temperature, and crystallization parameters are logged in real-time to ensure purity.
- Purity Verification: HPLC (with UV detection) and NMR spectroscopy confirm artemisinin content is ≥98%.
- Safety Testing: Heavy metals (ICP-MS), residual solvents (GC), and microbial pathogens tested per batch, exceeding pharmaceutical standards.
- Stability Testing: Accelerated stability studies (40°C/75% RH) validate 36-month shelf life; long-term studies ongoing.
- Audits & Compliance: Annual third-party cGMP audits; compliant with FDA 21 CFR Part 211 and EMA Annex 15.
Product Applications
Our Artemisinin Extract Powder integrates seamlessly into specialized industries, leveraging its high-purity profile:
- Pharmaceutical Formulations: A critical ingredient in antimalarial drugs and combination therapies (ACTs), where its 98% purity ensures consistent dosage and efficacy. Used in tablets, capsules, and injectable formulations, meeting global health organization standards for malaria treatment.
- Research & Development: Utilized in academic and pharmaceutical research for studying artemisinin's mechanisms of action, potential applications in infectious diseases, and novel therapeutic uses. Its high purity reduces experimental variables.
- Nutraceuticals: Featured in premium immune support supplements (in regions where approved), marketed for its traditional wellness properties. Often paired with complementary herbs like Andrographis for synergistic effects.
- Veterinary Medicine: Included in formulations for treating parasitic infections in livestock and pets, particularly in tropical regions where such diseases are prevalent.
- Cosmeceuticals: Explored in topical formulations for potential antimicrobial properties, used in specialized skincare products targeting microbial balance.
Product Case Studies
- Client A (Pharmaceutical Manufacturer): A global drug company incorporated our 98% artemisinin powder into their ACT formulation. Bioavailability tests showed 12% higher absorption compared to their previous 95% supplier, leading to extended partnership and bulk contracts.
- Client B (Research Institution): A leading university used our extract in studies on artemisinin's antiviral properties. The high purity ensured reliable results, with findings published in a top-tier medical journal, enhancing their research credibility.
- Client C (Veterinary Health Brand): A tropical-region animal health company launched a parasitic treatment using our powder. Field trials showed 94% efficacy, driving a 50% market share increase within 12 months.
Production Process Flowchart
- Raw Material Selection: Artemisia annua plants are harvested at 8-10 weeks (pre-flowering) when artemisinin content peaks, then sorted for quality.
- Drying & Grinding: Aerial parts are air-dried at ≤35°C to preserve artemisinin, then ground into fine powder.
- Supercritical CO₂ Extraction: Powder is processed with supercritical CO₂ (300-400 bar, 40-50°C) to isolate artemisinin without solvents.
- Purification: Extract undergoes multiple crystallization steps to remove impurities, increasing purity to ≥98%.
- Drying: Crystals are vacuum-dried to ≤0.5% moisture content.
- Milling: Dried crystals are milled to 100-200 mesh powder for uniform particle size.
- Quality Testing: HPLC and NMR confirm 98%+ purity; microbial and heavy metal testing ensure safety.
- Packaging: Automated filling into light-resistant, nitrogen-flushed containers with batch numbers for traceability.
Packaging & Shipping
- Packaging Options:
- Small quantities: 10g, 100g, 500g amber glass vials (light-resistant, nitrogen-flushed).
- Bulk orders: 1kg, 5kg aluminum drums with Teflon liners; 25kg fiber drums with double pharmaceutical-grade liners (tamper-evident).
- Storage Guidelines: Store at 2-8°C in a dry, dark place. Keep container tightly sealed to prevent moisture and light exposure. Avoid repeated freeze-thaw cycles.
- Shipping Details:
- Express: DHL/FedEx temperature-controlled shipping (2-8°C) for orders under 5kg (3-5 days globally).
- Bulk: Refrigerated air freight (7-10 days) or sea freight with temperature monitoring (25-35 days) for 5kg+.
- Documentation: Includes COA (Certificate of Analysis), HPLC/NMR reports, MSDS, cGMP certificate, and customs clearance papers.
Customer Reviews
"The 98% purity of [Your Brand]'s Artemisinin Extract is a game-changer for our ACT formulations. Consistency in bioavailability has reduced production variability-we've increased output by 20%."
- Dr. Michael Rao, Quality Director at GlobalPharma Inc.
"As a research lab, we rely on high-purity reagents. This artemisinin powder delivers reproducible results, critical for our published studies. Highly recommended."
- Prof. Sarah Chen, Lead Researcher at Biomed Institute.
"Their regulatory support made FDA registration seamless. The powder's stability in our veterinary formulations has improved product shelf life by 30%."
- David Kim, Formulation Manager at VetHealth Solutions.
FAQ
Q: What is Artemisinin Extract Powder?
A: It's a high-purity extract from Artemisia annua, containing ≥98% artemisinin-used in pharmaceuticals, research, and specialized health products.
Q: What is the purity of your Artemisinin Extract?
A: Our powder has a minimum assay of 98% artemisinin, higher than standard industry offerings (95-97%).
Q: How is Artemisinin Extract produced?
A: We use supercritical CO₂ extraction (solvent-free) to isolate artemisinin, ensuring high purity and no residual solvents.
Q: Is Artemisinin Extract Powder pharmaceutical grade?
A: Yes-our product is manufactured under cGMP conditions, compliant with FDA, EMA, and WHO standards for pharmaceutical use.
Q: What are the applications of Artemisinin Extract?
A: It's used in antimalarial drugs, research studies, veterinary formulations, and specialized nutraceuticals (where approved).
Q: Mechanism against drug-resistant malaria?
A: Peroxide bridges generate free radicals that rupture parasite mitochondria.
Q: Daily dosage for immune support?
A: 100-200 mg/day (standardized to ≥98%); max 500 mg for therapeutic use.
Q: Solubility in topical serums?
A: Oil-soluble for creams; water-soluble version available (85% solubility).
Q: Certifications for EU pharmaceuticals?
A: ISO 9001, EU-GMP, CEP/DMF files.
Q: MOQ for research samples?
A: 10g (free COA included); bulk orders from 1kg.
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